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The power of linkage analysis of a disease-related endophenotype using asymmetrically ascertained sib pairs
A linkage study of a qualitative disease endophenotype in a sample of sib pairs, consisting of one disease affected proband and one sibling is considered. The linkage statistic compares marker allele sharing with the proband in siblings with an abnormal endophenotype to siblings with the normal endo...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2658627/ https://ncbi.nlm.nih.gov/pubmed/20160849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csda.2008.08.030 |
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