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Necessary and sufficient conditions for equality of sibling and parent-offspring risk of a disease endophenotype in case families

A large number of linkage and association studies of complex diseases focus on analysis of a more common or more easily measured disease endophenotype. The motivation for this approach is that there is a pleiotropic locus common to both the disease and the endophenotype and that this locus is a majo...

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Bibliografische gegevens
Hoofdauteurs: SUNG, HEEJONG, MENDELL, NANCY R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242904/
https://ncbi.nlm.nih.gov/pubmed/22091704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2011.00685.x
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