SUG-1 Plays Proteolytic and Non-proteolytic Roles in the Control of Retinoic Acid Target Genes via Its Interaction with SRC-3

Nuclear retinoic acid receptor α (RARα) activates gene expression through dynamic interactions with coregulatory protein complexes, the assembly of which is directed by the ligand and the AF-2 domain of RARα. Then RARα and its coactivator SRC-3 are degraded by the proteasome. Recently it has emerged...

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Bibliographic Details
Main Authors: Ferry, Christine, Gianni, Maurizio, Lalevée, Sébastien, Bruck, Nathalie, Plassat, Jean-Luc, Raska, Ivan, Garattini, Enrico, Rochette-Egly, Cécile
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658106/
https://ncbi.nlm.nih.gov/pubmed/19144644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808815200
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