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Heparan Sulfate-modulated, Metalloprotease-mediated Sonic Hedgehog Release from Producing Cells

The ectodomains of numerous proteins are released from cells by matrix metalloproteases to yield soluble intercellular regulators. A disintegrin and metalloprotease (ADAM) family members have often been found to be the responsible “sheddases,” ADAM17/tumor necrosis factor-α-converting enzyme being i...

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Main Authors: Dierker, Tabea, Dreier, Rita, Petersen, Arnd, Bordych, Christian, Grobe, Kay
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658095/
https://ncbi.nlm.nih.gov/pubmed/19176481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806838200
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