The Non-coding RNA gadd7 Is a Regulator of Lipid-induced Oxidative and Endoplasmic Reticulum Stress

In obesity and diabetes, an imbalance in fatty acid uptake and fatty acid utilization leads to excess accumulation of lipid in non-adipose tissues. This lipid overload is associated with cellular dysfunction and cell death, which contribute to organ failure, a phenomenon termed lipotoxicity. To eluc...

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Bibliografiske detaljer
Main Authors: Brookheart, Rita T., Michel, Carlos I., Listenberger, Laura L., Ory, Daniel S., Schaffer, Jean E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
RNA-Mediated Regulation and Noncoding Rnas
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658040/
https://ncbi.nlm.nih.gov/pubmed/19150982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806209200
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