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Cocrystal structure of a class-I preQ(1) riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase
Riboswitches are mRNA domains that bind metabolites and modulate gene expression in cis. We report cocrystal structures of a remarkably compact riboswitch (34 nucleotides suffice for ligand recognition) from Bacillus subtilis selective for the essential nucleobase preQ(1) (7-aminomethyl-7-deazaguani...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657927/ https://ncbi.nlm.nih.gov/pubmed/19234468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1563 |
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