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E-cadherin dis-engagement activates the Rap1 GTPase
E-cadherin based adherens junctions are finely regulated by multiple cellular signaling events. Here we show that the Ras-related Rap1 GTPase is enriched in regions of nascent cell-cell contacts and strengthens E-cadherin junctions: constitutively active Rap1 expressing MDCK cells exhibit increased...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657844/ https://ncbi.nlm.nih.gov/pubmed/18767072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21902 |
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