E-cadherin dis-engagement activates the Rap1 GTPase

E-cadherin based adherens junctions are finely regulated by multiple cellular signaling events. Here we show that the Ras-related Rap1 GTPase is enriched in regions of nascent cell-cell contacts and strengthens E-cadherin junctions: constitutively active Rap1 expressing MDCK cells exhibit increased...

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Hlavní autoři: Asuri, Sirisha, Yan, Jingliang, Paranavitana, Nivanka C., Quilliam, Lawrence A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657844/
https://ncbi.nlm.nih.gov/pubmed/18767072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21902
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