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Nickel Compounds Induce Apoptosis in Human Bronchial Epithelial Beas-2B Cells by Activation of c-Myc through ERK Pathway
Nickel compounds are carcinogenic to humans and have been shown to alter epigenetic homeostasis. The c-Myc protein controls 15 % of human genes and it has been shown that fluctuations of c-Myc protein alter global epigenetic marks. Therefore, the regulation of c-Myc by nickel ions in immortalized bu...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657554/ https://ncbi.nlm.nih.gov/pubmed/19135467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.12.005 |
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