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Aeroallergen Der p 2 induces apoptosis of bronchial epithelial BEAS-2B cells via activation of both intrinsic and extrinsic pathway

BACKGROUND: Excessive apoptosis of airway epithelium is reported to induce airway remodeling and inhibited airway epithelium repair is highly associated with development of asthma and chronic obstructive pulmonary disease. Der p 2 is a major allergen derived from Dermatophagoides pteronyssinus and c...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Lin, Chun-Hsiang, Hong, Yu-Chuan, Kao, Shao-Hsuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687151/
https://ncbi.nlm.nih.gov/pubmed/26697166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0063-5
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