Antigen-specific B-1a antibodies induced by Francisella tularensis LPS provide long-term protection against F. tularensis LVS challenge

Francisella tularensis (Ft), a Gram-negative intracellular bacterium, is the etiologic agent of tularemia. Infection of mice with <10 Ft Live Vaccine Strain (Ft LVS) organisms i.p. causes a lethal infection that resembles human tularemia. Here, we show that immunization with as little as 0.1 ng F...

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Détails bibliographiques
Auteurs principaux: Cole, Leah E., Yang, Yang, Elkins, Karen L., Fernandez, Ellen T., Qureshi, Nilofer, Shlomchik, Mark J., Herzenberg, Leonard A., Herzenberg, Leonore A., Vogel, Stefanie N.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657382/
https://ncbi.nlm.nih.gov/pubmed/19251656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813411106
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