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Biodistribution of an oncolytic adenovirus after intracranial injection in permissive animals: a comparative study of Syrian hamsters and cotton rats

Conditionally replicative adenoviruses (CRAds) are often evaluated in mice; however, normal and cancerous mouse tissues are poorly permissive for human CRAds. As the cotton rat (CR) is a semipermissive animal and the Syrian hamster (SH) is a fully permissive model for adenoviral replication, we comp...

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Bibliographische Detailangaben
Hauptverfasser: Sonabend, AM, Ulasov, IV, Han, Y, Rolle, CE, Nandi, S, Cao, D, Tyler, MA, Lesniak, MS
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657193/
https://ncbi.nlm.nih.gov/pubmed/19011597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2008.80
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