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Commonly administered BCG strains including an evolutionarily early strain and evolutionarily late strains of disparate genealogy induce comparable protective immunity against tuberculosis

BCG has been administered to over 4 billion persons worldwide, but its efficacy in preventing tuberculosis in adults has been highly variable. One hypothesis for its variability is that different strains of BCG vary in protective efficacy, and moreover, that evolutionarily early strains are more eff...

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Detalles Bibliográficos
Main Authors: Horwitz, Marcus A., Harth, Günter, Dillon, Barbara Jane, Masleša-Gali, Saša
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657049/
https://ncbi.nlm.nih.gov/pubmed/19007841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.10.058
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