Proteomic analysis of tumor necrosis factor-α resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype

INTRODUCTION: Despite intensive study of the mechanisms of chemotherapeutic drug resistance in human breast cancer, few reports have systematically investigated the mechanisms that underlie resistance to the chemotherapy-sensitizing agent tumor necrosis factor (TNF)-α. Additionally, the relationship...

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Hauptverfasser: Zhou, Changhua, Nitschke, Ashley M, Xiong, Wei, Zhang, Qiang, Tang, Yan, Bloch, Michael, Elliott, Steven, Zhu, Yun, Bazzone, Lindsey, Yu, David, Weldon, Christopher B, Schiff, Rachel, McLachlan, John A, Beckman, Barbara S, Wiese, Thomas E, Nephew, Kenneth P, Shan, Bin, Burow, Matthew E, Wang, Guangdi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656902/
https://ncbi.nlm.nih.gov/pubmed/19087274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2210
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