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Increased expression of lipocalin-type prostaglandin D(2 )synthase in osteoarthritic cartilage

INTRODUCTION: Prostaglandin D synthase (PGDS) is responsible for the biosynthesis of PGD and J series, which have been shown to exhibit anti-inflammatory and anticatabolic effects. Two isoforms have been identified: hematopoietic- and lipocalin-type PGDS (H-PGDS and L-PGDS, respectively). The aims o...

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Autores principales: Zayed, Nadia, Li, Xinfang, Chabane, Nadir, Benderdour, Mohamed, Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Duval, Nicolas, Fahmi, Hassan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656251/
https://ncbi.nlm.nih.gov/pubmed/19094210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2581
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