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Histone H3 Lys79 methylation is required for efficient nucleotide excision repair in a silenced locus of Saccharomyces cerevisiae

Methylation of specific histone lysine residues regulates gene expression and heterochromatin function, but little is known about its role in DNA repair. To examine how changes in conserved methylated residues of histone H3 affect nucleotide excision repair (NER), viable H3K4R and H3K79R mutants wer...

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Autors principals: Chaudhuri, Shubho, Wyrick, John J., Smerdon, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655692/
https://ncbi.nlm.nih.gov/pubmed/19155276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp003
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