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Quality Control of a Transcriptional Regulator by SUMO-Targeted Degradation
Slx5 and Slx8 are heterodimeric RING domain-containing proteins that possess SUMO-targeted ubiquitin ligase (STUbL) activity in vitro. Slx5-Slx8 and its orthologs are proposed to target SUMO conjugates for ubiquitin-mediated proteolysis, but the only in vivo substrate identified to date is mammalian...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655623/ https://ncbi.nlm.nih.gov/pubmed/19139279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01470-08 |
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