A Tautomerase-Null Macrophage Migration-Inhibitory Factor (MIF) Gene Knock-In Mouse Model Reveals That Protein Interactions and Not Enzymatic Activity Mediate MIF-Dependent Growth Regulation

Macrophage migration-inhibitory factor (MIF) is an upstream regulator of innate immunity and a potential molecular link between inflammation and cancer. The unusual structural homology between MIF and certain tautomerases, which includes both a conserved substrate-binding pocket and a catalytic N-te...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Główni autorzy: Fingerle-Rowson, Günter, Kaleswarapu, Dayananda Rao, Schlander, Corinna, Kabgani, Nazanin, Brocks, Tania, Reinart, Nina, Busch, Raymonde, Schütz, Anke, Lue, Hongqi, Du, Xin, Liu, Aihua, Xiong, Huabao, Chen, Yibang, Nemajerova, Alice, Hallek, Michael, Bernhagen, Jürgen, Leng, Lin, Bucala, Richard
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology (ASM) 2009
Hasła przedmiotowe:
Articles
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655604/
https://ncbi.nlm.nih.gov/pubmed/19188446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01907-08
Etykiety: Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!

Podobne zapisy