Generation of Herpesvirus Entry Mediator (HVEM)-Restricted Herpes Simplex Virus Type 1 Mutant Viruses: Resistance of HVEM-Expressing Cells and Identification of Mutations That Rescue Nectin-1 Recognition

Both initial infection and cell-to-cell spread by herpes simplex virus type 1 (HSV-1) require the interaction of the viral glycoprotein D (gD) with an entry receptor on the cell surface. The two major HSV entry receptors, herpesvirus entry mediator (HVEM) and nectin-1, mediate infection independentl...

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Detalhes bibliográficos
Main Authors: Uchida, Hiroaki, Shah, Waris A., Ozuer, Ali, Frampton, Arthur R., Goins, William F., Grandi, Paola, Cohen, Justus B., Glorioso, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655597/
https://ncbi.nlm.nih.gov/pubmed/19129446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01449-08
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