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Identifying Sites Bound by Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) in the Human Genome: Defining a Position-Weighted Matrix To Predict Sites Bound by EBNA1 in Viral Genomes

We identified binding sites for Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) in the human genome using chromatin immunoprecipitation and microarrays. The sequences for these newly identified sites were used to generate a position-weighted matrix (PWM) for EBNA1's DNA-binding sites. This P...

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Main Authors: Dresang, Lindsay R., Vereide, David T., Sugden, Bill
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655553/
https://ncbi.nlm.nih.gov/pubmed/19129441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01974-08
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