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The AT-hook DNA binding ability of the Epstein Barr Virus EBNA1 protein is necessary for the maintenance of viral genomes in latently infected cells

Epstein Barr Virus (EBV) is a human tumor virus that is causally linked to malignancies such as Burkitt’s lymphoma, and gastric and nasopharyngeal carcinomas. Tethering of EBV genomes to cellular chromosomes is required for the synthesis and persistence of viral plasmids in tumor cells. However, it...

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Библиографические подробности
Опубликовано в: :Virology
Главные авторы: Chakravorty, Adityarup, Sugden, Bill
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567472/
https://ncbi.nlm.nih.gov/pubmed/26122471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.05.018
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