The Molecular Alarmone (p)ppGpp Mediates Stress Responses, Vancomycin Tolerance, and Virulence in Enterococcus faecalis

The stringent response is a global bacterial response to stress that is mediated by accumulation of the alarmone (p)ppGpp. In this study, treatment with mupirocin was shown to induce high levels of (p)ppGpp production in Enterococcus faecalis, indicating that this nosocomial pathogen can mount a cla...

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Bibliografiske detaljer
Main Authors: Abranches, Jacqueline, Martinez, Alaina R., Kajfasz, Jessica K., Chávez, Violeta, Garsin, Danielle A., Lemos, José A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Molecular Biology of Pathogens
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655485/
https://ncbi.nlm.nih.gov/pubmed/19168608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01726-08
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