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Voltage-dependent gating of NR1/2B NMDA receptors

Ligand-gated ion channels are activated by agonist binding, but may also be modulated by membrane voltage. N-Methyl-d-aspartate receptors (NMDARs) exhibit especially strong voltage dependence due to channel block by external Mg(2+) ([Formula: see text]). Here we demonstrate that activity of NMDARs c...

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Bibliografiske detaljer
Main Authors: Clarke, Richard J, Johnson, Jon W
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655412/
https://ncbi.nlm.nih.gov/pubmed/18936081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.160622
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