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Endothelium-dependent contractions: when a good guy turns bad!

Endothelial cells can induce contractions of the underlying vascular smooth muscle by generating vasoconstrictor prostanoids (endothelium-dependent contracting factor; EDCF). The endothelial COX-1 isoform of cyclooxygenase appears to play the dominant role in the phenomenon. Its activation requires...

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Bibliografiske detaljer
Main Authors: Vanhoutte, Paul M, Tang, Eva H C
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655387/
https://ncbi.nlm.nih.gov/pubmed/18818246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.161430
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