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Stereoselective, Dual-Mode Ruthenium-Catalyzed Ring-Expansion of Alkynylcyclopropanols

A novel, dual-pathway ring-expansion of alkynylcyclopropanols is described. On treatment with a ruthenium catalyst, these compounds undergo highly selective enlargement to either (Z)-alkylidene cyclobutanones or β-substituted cyclopentenones. The unique ability to access the least selective double b...

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Autori principali: Trost, Barry M., Xie, Jia, Maulide, Nuno
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655345/
https://ncbi.nlm.nih.gov/pubmed/19053484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja807894t
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