Ablation of SP-A has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: sex differences

BACKGROUND: Surfactant protein A (SP-A) enhances phagocytosis of bacteria, including Klebsiella pneumoniae, by alveolar macrophages. Ozone, a major air pollutant, can cause oxidation of surfactant and may influence lung immune function. Immune function may also be affected by sex-specific mechanisms...

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Detalhes bibliográficos
Main Authors: Mikerov, Anatoly N, Haque, Rizwanul, Gan, Xiaozhuang, Guo, Xiaoxuan, Phelps, David S, Floros, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655296/
https://ncbi.nlm.nih.gov/pubmed/19055785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-77
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