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Esc2 and Sgs1 Act in Functionally Distinct Branches of the Homologous Recombination Repair Pathway in Saccharomyces cerevisiae

Esc2 is a member of the RENi family of SUMO-like domain proteins and is implicated in gene silencing in Saccharomyces cerevisiae. Here, we identify a dual role for Esc2 during S-phase in mediating both intra-S-phase DNA damage checkpoint signaling and preventing the accumulation of Rad51-dependent h...

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Detalhes bibliográficos
Main Authors: Mankouri, Hocine W., Ngo, Hien-Ping, Hickson, Ian D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655263/
https://ncbi.nlm.nih.gov/pubmed/19158388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0877
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