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Does Damage to DNA and Other Macromolecules Play a Role in Aging? If So, How?

One of the most pervasive ideas regarding the causes of aging is that longevity is constrained in large measure by damage to macromolecules. An increasing body of cellular and molecular data, generated over the past decade or so, has generally supported this “damage accumulation” hypothesis of aging...

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Detalhes bibliográficos
Main Authors: Campisi, Judith, Vijg, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655027/
https://ncbi.nlm.nih.gov/pubmed/19228786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gln065
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