Postnatal Estradiol Up-regulates Lung Nitric Oxide Synthases and Improves Lung Function in Bronchopulmonary Dysplasia

Rationale: Nitric oxide (NO) plays an important role in lung development and perinatal lung function, and pulmonary NO synthases (NOS) are decreased in bronchopulmonary dysplasia (BPD) following preterm birth. Fetal estradiol levels increase during late gestation and estradiol up-regulates NOS, sugg...

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Main Authors: McCurnin, Donald C., Pierce, Richard A., Willis, Brigham C., Chang, Ling Yi, Yoder, Bradley A., Yuhanna, Ivan S., Ballard, Philip L., Clyman, Ronald I., Waleh, Nahid, Maniscalco, William, Crapo, James D., Grubb, Peter H., Shaul, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2009
Assuntos:
E. Pediatrics and Lung Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654978/
https://ncbi.nlm.nih.gov/pubmed/19151197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200805-794OC
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