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Patent ductus arteriosus ligation alters pulmonary gene expression in preterm baboons

Ibuprofen-induced ductus closure improves pulmonary mechanics and increases alveolar surface area in premature baboons compared with baboons with a persistent patent ductus arteriosus (PDA). Ibuprofen-treatment has no effect on the expression of genes that regulate pulmonary inflammation but does in...

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Detalhes bibliográficos
Main Authors: Waleh, Nahid, McCurnin, Donald C., Yoder, Bradley A., Shaul, Philip W., Clyman, Ronald I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065199/
https://ncbi.nlm.nih.gov/pubmed/21131894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3182084f8d
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