Genome and gene alterations by insertions and deletions in the evolution of human and chimpanzee chromosome 22

BACKGROUND: Understanding structure and function of human genome requires knowledge of genomes of our closest living relatives, the primates. Nucleotide insertions and deletions (indels) play a significant role in differentiation that underlies phenotypic differences between humans and chimpanzees....

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Bibliographic Details
Main Authors: Volfovsky, Natalia, Oleksyk, Taras K, Cruz, Kristine C, Truelove, Ann L, Stephens, Robert M, Smith, Michael W
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654908/
https://ncbi.nlm.nih.gov/pubmed/19171065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-51
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