Paracrine sonic hedgehog signalling by prostate cancer cells induces osteoblast differentiation

BACKGROUND: Sonic hedgehog (Shh) and components of its signalling pathway have been identified in human prostate carcinoma and increased levels of their expression appear to correlate with disease progression and metastasis. The mechanism through which Shh signalling could promote metastasis in bone...

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Detalhes bibliográficos
Main Authors: Zunich, Samantha M, Douglas, Taneka, Valdovinos, Maria, Chang, Tiffany, Bushman, Wade, Walterhouse, David, Iannaccone, Philip, Lamm, Marilyn LG
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654862/
https://ncbi.nlm.nih.gov/pubmed/19254376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-12
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