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Functions of the Type 1 BMP Receptor Acvr1 (Alk2) in Lens Development: Cell Proliferation, Terminal Differentiation, and Survival

PURPOSE: Bone morphogenetic protein (BMP) signaling is essential for the induction and subsequent development of the lens. The purpose of this study was to analyze the function(s) of the type 1 BMP receptor, Acvr1, in lens development. METHODS: Acvr1 was deleted from the surface ectoderm of mouse em...

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Autors principals: Rajagopal, Ramya, Dattilo, Lisa K., Kaartinen, Vesa, Deng, Chu-Xia, Umans, Lieve, Zwijsen, An, Roberts, Anita B., Bottinger, Erwin P., Beebe, David C.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654711/
https://ncbi.nlm.nih.gov/pubmed/18566469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2217
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