Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits

BACKGROUND: Several studies in multiple ethnicities have reported linkage to type 2 diabetes on chromosome 1q21-25. Both PKLR encoding the liver pyruvate kinase and NOS1AP encoding the nitric oxide synthase 1 (neuronal) adaptor protein (CAPON) are positioned within this chromosomal region and are th...

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Autori principali: Andreasen, Camilla Helene, Mogensen, Mette Sloth, Borch-Johnsen, Knut, Sandbæk, Annelli, Lauritzen, Torsten, Almind, Katrine, Hansen, Lars, Jørgensen, Torben, Pedersen, Oluf, Hansen, Torben
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654670/
https://ncbi.nlm.nih.gov/pubmed/19111066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-118
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