The Type 2 Diabetes Associated Minor Allele of rs2237895 KCNQ1 Associates with Reduced Insulin Release Following an Oral Glucose Load

BACKGROUND: Polymorphisms in the potassium channel, voltage-gated, KQT-like subfamily, member 1 (KCNQ1) have recently been reported to associate with type 2 diabetes. The primary aim of the present study was to investigate the putative impact of these KCNQ1 polymorphisms (rs2283228, rs2237892, rs223...

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Detalhes bibliográficos
Main Authors: Holmkvist, Johan, Banasik, Karina, Andersen, Gitte, Unoki, Hiroyuki, Jensen, Thomas Skot, Pisinger, Charlotta, Borch-Johnsen, Knut, Sandbæk, Annelli, Lauritzen, Torsten, Brunak, Sören, Maeda, Shiro, Hansen, Torben, Pedersen, Oluf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689931/
https://ncbi.nlm.nih.gov/pubmed/19516902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005872
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