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Heparanase Regulates Levels of Syndecan-1 in the Nucleus

Syndecan-1 is a transmembrane heparan sulfate-bearing proteoglycan known to regulate multiple biological functions at the cell surface and within the extracellular matrix. Its functional activity can be modulated by heparanase, an enzyme that cleaves heparan sulfate chains and whose expression has b...

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Autors principals: Chen, Ligong, Sanderson, Ralph D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654539/
https://ncbi.nlm.nih.gov/pubmed/19305494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004947
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