HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression

BACKGROUND: RNA interference is a gene regulatory mechanism that employs small RNA molecules such as microRNA. Previous work has shown that HIV-1 produces TAR viral microRNA. Here we describe the effects of the HIV-1 TAR derived microRNA on cellular gene expression. RESULTS: Using a variation of sta...

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Bibliografiske detaljer
Main Authors: Klase, Zachary, Winograd, Rafael, Davis, Jeremiah, Carpio, Lawrence, Hildreth, Richard, Heydarian, Mohammad, Fu, Sidney, McCaffrey, Timothy, Meiri, Eti, Ayash-Rashkovsky, Mila, Gilad, Shlomit, Bentwich, Zwi, Kashanchi, Fatah
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654423/
https://ncbi.nlm.nih.gov/pubmed/19220914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-18
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