HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR

BACKGROUND: RNA interference (RNAi) is a regulatory mechanism conserved in higher eukaryotes. The RNAi pathway generates small interfering RNA (siRNA) or micro RNA (miRNA) from either long double stranded stretches of RNA or RNA hairpins, respectively. The siRNA or miRNA then guides an effector comp...

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Detalhes bibliográficos
Main Authors: Klase, Zachary, Kale, Prachee, Winograd, Rafael, Gupta, Madhur V, Heydarian, Mohammad, Berro, Reem, McCaffrey, Timothy, Kashanchi, Fatah
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955452/
https://ncbi.nlm.nih.gov/pubmed/17663774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-63
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