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Kinetic and X-Ray Structural Evidence for Negative Cooperativity in Substrate Binding to Nicotinate Mononucleotide Adenylyltransferase (NMAT) from Bacillus anthracis

Biosynthesis of NAD(P) in bacteria occurs through either the de novo or one of the salvage pathways which converge at the point where the reaction of nicotinate mononucleotide (NaMN) with adenosine triphosphate (ATP), is coupled to the formation of nicotinate adenine dinucleotide (NaAD) and inorgani...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sershon, Valerie C., Santarsiero, Bernard D., Mesecar, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654404/
https://ncbi.nlm.nih.gov/pubmed/18977360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.037
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