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Cardiovascular and Hematopoietic Defects Associated With Notch1 Activation in Embryonic Tie2-Expressing Populations

Notch signaling is critical for the development and maintenance of the cardiovasculature, with loss-of-function studies defining roles of Notch1 in the endothelial/hematopoietic lineages. No in vivo studies have addressed complementary gain-of-function strategies within these tissues to define conse...

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Detalhes bibliográficos
Main Authors: Venkatesh, Deepak A., Park, Kyung-Sook, Harrington, Anne, Miceli-Libby, Laura, Yoon, Jeong K., Liaw, Lucy
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654335/
https://ncbi.nlm.nih.gov/pubmed/18617694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.177808
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