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Novel dimethoxy(aminoalkoxy)borate derived from (S)-diphenylprolinol as highly efficient catalyst for the enantioselective boron-mediated reduction of prochiral ketones

The novel dimethoxyl(aminoalkoxy)borate 1 was isolated as a white crystalline dimer joined by H–bonding as evidenced by X-ray analysis, and demonstrated to be a highly effective catalyst for the asymmetric reduction of representative prochiral ketones with borane-DMS. Optically pure alcohols were ob...

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Detalhes bibliográficos
Main Authors: Stepanenko, Viatcheslav, Ortiz-Marciales, Margarita, Barnes, Charles L., Garcia, Carmelo
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654321/
https://ncbi.nlm.nih.gov/pubmed/20160845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.12.061
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