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pH Dependent Mechanism of Nitric Oxide Release in Nitrophorins 2 and 4

Nitrophorins are NO carrier proteins that transport and release NO through a pH dependent conformational change. They bind NO tightly in a low pH environment and release it in a higher pH environment. Experimental evidence shows that the increase in the NO dissociation equilibrium constant, K(d), is...

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Autors principals: Swails, Jason M., Meng, Yilin, Walker, F. Ann, Marti, Marcelo A., Estrin, Dario A., Roitberg, Adrian E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654266/
https://ncbi.nlm.nih.gov/pubmed/19159340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp806906x
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