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Expanding Circle of Inhibition: Small-Molecule Inhibitors of Bcl-2 as Anticancer Cell and Antiangiogenic Agents

The specific targeting of diseases, particularly cancer, is a primary aim in drug development, as specificity reduces unwelcome effects on healthy tissue and increases drug efficacy at the target site. Drug specificity can be increased by improving the delivery system or by selecting drugs with affi...

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Detalhes bibliográficos
Main Authors: Zeitlin, Benjamin D., Zeitlin, Isaac J., Nör, Jacques E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654265/
https://ncbi.nlm.nih.gov/pubmed/18757333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.15.7693
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