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The non-discriminating aspartyl-tRNA synthetase from Helicobacter pylori: Anticodon-binding domain mutations that impact tRNA specificity and heterologous toxicity
Divergent tRNA substrate recognition patterns distinguish the two distinct forms of aspartyl-tRNA synthetase (AspRS) that exist in different bacteria. In some cases, a canonical, discriminating AspRS (D-AspRS) specifically generates Asp-tRNA(Asp) and usually co-exists with asparaginyl-tRNA synthetas...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654173/ https://ncbi.nlm.nih.gov/pubmed/16800632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060189c |
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