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Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ

Telomeres protect chromosome ends from being viewed as double-strand breaks and from eliciting a DNA damage response. Deprotection of chromosome ends occurs when telomeres become critically short because of replicative attrition or inhibition of TRF2. In this study, we report a novel form of deprote...

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Detalhes bibliográficos
Main Authors: Hsiao, Susan J., Smith, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654126/
https://ncbi.nlm.nih.gov/pubmed/19221198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200810132
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