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Distinct Cellular and Molecular Mechanisms Underlie Functional Remodeling of Repolarizing K(+) Currents With Left Ventricular Hypertrophy

Left ventricular hypertrophy (LVH) is associated with electric remodeling and increased arrhythmia risk, although the underlying mechanisms are poorly understood. In the experiments here, functional voltage-gated (Kv) and inwardly rectifying (Kir) K(+) channel remodeling was examined in a mouse mode...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marionneau, Céline, Brunet, Sylvain, Flagg, Thomas P., Pilgram, Thomas K., Demolombe, Sophie, Nerbonne, Jeanne M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653713/
https://ncbi.nlm.nih.gov/pubmed/18451341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.170050
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