Distinct Cellular and Molecular Mechanisms Underlie Functional Remodeling of Repolarizing K(+) Currents With Left Ventricular Hypertrophy

Left ventricular hypertrophy (LVH) is associated with electric remodeling and increased arrhythmia risk, although the underlying mechanisms are poorly understood. In the experiments here, functional voltage-gated (Kv) and inwardly rectifying (Kir) K(+) channel remodeling was examined in a mouse mode...

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Bibliografiske detaljer
Main Authors: Marionneau, Céline, Brunet, Sylvain, Flagg, Thomas P., Pilgram, Thomas K., Demolombe, Sophie, Nerbonne, Jeanne M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653713/
https://ncbi.nlm.nih.gov/pubmed/18451341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.170050
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