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Signatures of Selection in Fusion Transcripts Resulting From Chromosomal Translocations in Human Cancer

BACKGROUND: The recurrence and non-random distribution of translocation breakpoints in human tumors are usually attributed to local sequence features present in the vicinity of the breakpoints. However, it has also been suggested that functional constraints might contribute to delimit the position o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ortiz de Mendíbil, Iñigo, Vizmanos, José L., Novo, Francisco J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653638/
https://ncbi.nlm.nih.gov/pubmed/19279687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004805
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