RhoGDIβ-induced hypertrophic growth in H9c2 cells is negatively regulated by ZAK

We found that overexpression of RhoGDIβ, a Rho GDP dissociation inhibitor, induced hypertrophic growth and suppressed cell cycle progression in a cultured cardiomyoblast cell line. Knockdown of RhoGDIβ expression by RNA interference blocked hypertrophic growth. We further demonstrated that RhoGDIβ p...

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Detalhes bibliográficos
Main Authors: Huang, Chih-Yang, Yang, Li-Chiu, Liu, Kuan-Yu, Liao, Pao-Hsin, Chou, Janet Ing-Yuh, Chou, Ming-Yung, Lin, Wei-Wen, Yang, Jaw-Ji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653512/
https://ncbi.nlm.nih.gov/pubmed/19272173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-16-11
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