Del(6)(q22) and BCL6 Rearrangements in Primary CNS Lymphoma Are Indicators of an Aggressive Clinical Course

PURPOSE: Primary CNS lymphoma (PCNSL) is an aggressive lymphoma but clinically validated biologic markers that can predict natural history to tailor treatment according to risk are lacking. Several genetic changes including BCL6 rearrangements and deletion of 6q22, containing the putative tumor supp...

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Main Authors: Cady, Francois M., O'Neill, Brian Patrick, Law, Mark E., Decker, Paul A., Kurtz, David M., Giannini, Caterina, Porter, Alyx B., Kurtin, Paul J., Johnston, Patrick B., Dogan, Ahmet, Remstein, Ellen D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2008
Fag:
Lymphoma and Myeloma
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653136/
https://ncbi.nlm.nih.gov/pubmed/18645192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.16.1455
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