Del(6)(q22) and BCL6 Rearrangements in Primary CNS Lymphoma Are Indicators of an Aggressive Clinical Course

PURPOSE: Primary CNS lymphoma (PCNSL) is an aggressive lymphoma but clinically validated biologic markers that can predict natural history to tailor treatment according to risk are lacking. Several genetic changes including BCL6 rearrangements and deletion of 6q22, containing the putative tumor supp...

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Detalhes bibliográficos
Main Authors: Cady, Francois M., O'Neill, Brian Patrick, Law, Mark E., Decker, Paul A., Kurtz, David M., Giannini, Caterina, Porter, Alyx B., Kurtin, Paul J., Johnston, Patrick B., Dogan, Ahmet, Remstein, Ellen D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2008
Assuntos:
Lymphoma and Myeloma
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653136/
https://ncbi.nlm.nih.gov/pubmed/18645192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.16.1455
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